Mental Illness
Common in Returning Soldiers
High rates of mental health disorders are
being diagnosed among US military personnel soon after being
released from duty in Iraq and Afghanistan, according to
investigators in San Francisco. They estimate that out of
103,788 returning veterans, 25 percent had a mental health
diagnosis, and more than half of these patients had two or
more distinct conditions....
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Heart
Disease, Diabetes, Depression a Deadly Mix
Heart disease, diabetes and depression can be
a lethal triple-play -- boosting a patient's death risk by 20
percent to 30 percent, new research shows. "We do not know
what this increased risk is due to, but it could either be
that depression influences crucial aspects of self-care
behaviors needed to manage diabetes or that a more severe
disease process is reflected in more depressive symptoms,"
said lead researcher Anastasia Georgiades, a research
associate in the department of psychiatry and behavioral
science at Duke University in Durham, N.C...
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Depression Hits U.S. Blacks Harder Than Whites
Black Americans are more likely than whites
to suffer severe, untreated and disabling depression, U.S.
research shows. Researchers at the Harvard School of Public
Health analyzed data on 6,082 people who took part in a
national survey conducted between 2001 and 2003. They found
that 17.9 percent of white Americans had depression at some
point in their lives, compared with 10.4 percent of blacks of
African descent and 12.9 percent of blacks of West Indian or
Caribbean descent...
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Heart Healthy Flax Seed May Also be Beneficial in Promoting a
Better Mood
A recent scientific
finding suggests that flax seeds can help with mood and
depression and Greatplainsflax.com adds flax seed starter
packages to its selection of golden omega flax seed products.
At the annual meeting of the American Psychosomatic Society in
Budapest, Hungary Dr. Sarah M. Conklin, a postdoctoral scholar
in the department of psychiatry at the University of
Pittsburgh School of Medicine reported that omega-3
polyunsaturated fatty acids, found in salmon and flax seed may
affect parts of the brain related to emotion...
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Men on Antidepressants Drink Less Often
Antidepressant
medication may help depressed men cut down on their drinking,
but the same may not be true of women, a new study suggests.
In a survey of more than 14,000 adults, Canadian researchers
found that respondents with major depression tended to drink
more than non-depressed men and women. However, this was not
the case for depressed men who were on antidepressant
medication. Among women, on the other hand, those with
depression drank more regardless of whether they were taking
an antidepressant...
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Corcept
Therapeutics Announces Phase 3 Study Evaluating CORLUX(R) for
Psychotic Major Depression Misses Primary Endpoint
Corcept Therapeutics
Incorporated (NASDAQ: CORT) today announced that Study 06, the
last of three Phase 3 trials evaluating CORLUX for treating
the psychotic features of Psychotic Major Depression (PMD),
did not achieve statistical significance with respect to its
primary endpoint. However, there was a statistically
significant correlation between plasma levels and clinical
outcome achieved during treatment. Further, the company
reported that the incidence of serious adverse events did not
differ between placebo and any of the three CORLUX dose groups...
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Social Stress May Kill Off New Brain Cells
Research in rats
shows that a single, socially stressful situation may
contribute to depression by killing new nerve cells in the
hippocampus, the area of the brain that processes learning,
memory and emotion. In young rats, the stress of encountering
older, aggressive rats didn't stop the creation of new brain
nerve cells, the first step in a process called neurogenesis.
However, this form of stress did prevent many new nerve cells
from surviving, which left the young rats with fewer neurons
for processing feelings and emotions...
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Alcohol: How much is bad for you?
I am often asked if
a glass of wine is ok if you are on medications. My standard
answer--you shouldn't do it--isn't rigorous, and a better
answer might be that alcohol's effects are magnified. Part of
the problem is that a "drink" isn't the same to everyone.
Different countries have different "standard drinks" ranging,
usually, from 10g to 14g per drink. As a reference point,
there are about 14g in a 12 oz beer (5% alcohol by volume) and
77g in a bottle of wine (13% alcohol by volume.) So there are
about six "drinks" in a bottle of wine...
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CeNeRx BioPharma Announces Positive Phase I Results in First
Human Trial of Third Generation RIMA Antidepressant
CeNeRx BioPharma,
Inc., a clinical stage company developing and commercializing
innovative treatments for diseases of the central nervous
system, today announced top-line results from a Phase I
clinical trial of Tyrima(TM), its lead candidate for the
treatment of depression and anxiety. In this study, Tyrima was
safe and well tolerated. Tyrima is a member of a novel class
of drugs known as reversible inhibitors of monoamine oxidase
A, or RIMAs...
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Pain Complicates Depression Treatment in Elderly
By interfering with
normal activities, chronic pain can impede recovery from
depression in older adults, according to findings reported in
the Journal of the American Geriatrics Society. Dr. Shahrzad
Mavandadi, of the University of Pennsylvania, Philadelphia,
and colleagues examined the effects of pain on the response to
depression treatment in 524 men, 60 years of age or older, who
were seen at a VA medical center...
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Adolescent Depression and High Receptivity to Tobacco Ads May
Lead to Teen Smoking
A NIDA-funded study
by researchers at the Georgetown University School of Medicine
and the University of Pennsylvania School of Medicine reports
that adolescent depression, combined with high receptivity to
tobacco advertising, plays a powerful role in whether a teen
smokes cigarettes. While research has demonstrated the effects
of a number of factors on adolescent smoking behavior
(including exposure to smoking by family and friends, high
receptivity to tobacco advertising, and positive attitudes and
beliefs about smoking), this is one of the first studies to
examine how depression combines with these factors to
influence the likelihood of smoking...
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Depression Worsens Outcomes for Heart Failure Patients
Depression is a
major factor in poor medical outcomes for heart failure
patients, says a new U.S. study. The study, conducted by
researchers at Duke University Medical Center and the
University of North Carolina, included 204 heart failure
patients who were followed for an average of three years.
Tests showed that 46 percent of the patients had significant
symptoms of depression. During the study period, 26 percent of
the patients died, and 48 percent were hospitalized at least
once for their heart condition...
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Canadians and Americans Urged to Demand That Physicians Use
Guidelines to Treat Patients with Depression
Canadians and
Americans must "raise their voice and demand basic standards
of care for those suffering depression and other common mental
disorders." Bill Wilkerson, Co-Founder and CEO of the Global
Business and Economic Roundtable on Addiction and Mental
Health, says "below standard medical care is the standard for
mental illnesses." In a speech to be delivered on Wednesday
morning (March 7th) to the "Bottom Line" Mental Health
conference, Wilkerson says that in both the United States and
Canada, fewer than half and closer to one-quarter of those
treated for depression receive guideline-level care...
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Treating
Depression Improves Diabetes Control
A study of type 2
diabetics with depression confirms that depression has a
negative impact on glycemic (blood sugar) control, researchers
report, and "affirms the importance of depression management
in diabetic patients in its potential to improve glycemic
control." Researchers from Missouri treated 93 patients with
type 2 diabetes and depression with the antidepressant
bupropion (Wellbutrin). "We selected bupropion because it is
capable of reducing depression and weight simultaneously and
hypothesized that these effects would be accompanied by
improved glycemic control in diabetic patients with major
depressive disorder," the team explains in the journal
Diabetes Care...
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